Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 15/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378258 | 0.77 | XIAP (0.42) | XIAPBIRC2TAAR1 | |
| SCHEMBL13907113 | 0.69 | XIAP (0.40) | XIAPBIRC2 | |
| SCHEMBL28069679 | 0.68 | PLA2G4A (0.37) | NPC1RAB9ASMN1; SMN2PLA2G4A | |
| SCHEMBL6840495 | 0.68 | HSD17B10 (0.43) | NPC1RAB9ASMN1; SMN2PLA2G4A | |
| SCHEMBL2645328 | 0.67 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26882860 | 0.67 | CYP1A2 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31596034 | 0.66 | PLA2G4A (0.41) | NPC1RAB9ASMN1; SMN2PLA2G4A | |
| SCHEMBL21722413 | 0.66 | PLA2G4A (0.41) | NPC1RAB9ASMN1; SMN2PLA2G4A | |
| SCHEMBL21861642 | 0.66 | TRPA1 (0.53) | XIAPBIRC2 | |
| SCHEMBL20390889 | 0.66 | XIAP (0.43) | XIAPBIRC2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022313-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |