Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15589680 | 0.89 | MAOB (0.43) | CTSVCTSLMAOBALDH1A1KDM4E | |
| SCHEMBL19159330 | 0.89 | SIRT2 (0.44) | CTSVCTSLMAOBKDM4ESIRT2 | |
| SCHEMBL7381558 | 0.85 | CTSV (0.52) | CTSVCTSLMAOBALDH1A1KDM4E | |
| SCHEMBL19160125 | 0.82 | LTA4H (0.46) | MAOBKDM4ESMN1; SMN2LTA4HMEN1 | |
| SCHEMBL7374213 | 0.80 | MAPT (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL28302706 | 0.80 | PDK1 (0.57) | CTSVCTSLMAOBALDH1A1KDM4E | |
| SCHEMBL5956241 | 0.79 | KDM4E (0.56) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL22762667 | 0.78 | KDM4E (0.60) | CTSVCTSLMAOBALDH1A1KDM4E | |
| SCHEMBL646567 | 0.77 | BRD4 (0.42) | — | |
| SCHEMBL3916435 | 0.77 | LTA4H (0.39) | LTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171166-A1 | BENZODIAZEPINE DERIVATIVES FOR IMAGING THROMBI | Diatide, Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6171578-B1 | GLYCOPROTEIN IIB/IIIA RECEPTOR-BINDING BENZODIAZEPINE DERIVATIVES COVALENTLY LINKED TO METAL ION CHELATORS. | DIATIDE, INC. | 2001-01-09 | — | — | US | disclosed |
| WO-2000061195-A1 | BENZODIAZEPINE DERIVATIVES FOR IMAGING THROMBI | DIATIDE, INC. (US) | 2000-10-19 | — | — | WO | disclosed |