Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 11/20 | 0.34 |
| ▸ | JAK2 | O60674 | 10/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376052 | 0.88 | CTSL (0.36) | CTSL | |
| SCHEMBL319130 | 0.81 | PPIA (0.33) | CTSL | |
| SCHEMBL7418004 | 0.79 | PPIA (0.41) | CTSLCTSSCTSKCTSB | |
| SCHEMBL319692 | 0.77 | CTSL (0.35) | CTSLCTSK | |
| SCHEMBL7428389 | 0.77 | PPIA (0.35) | CTSL | |
| SCHEMBL7369194 | 0.77 | PPIA (0.39) | CTSL | |
| SCHEMBL7424937 | 0.77 | PPIA (0.38) | CTSLJAK1JAK2 | |
| SCHEMBL7394465 | 0.75 | HPGDS (0.40) | CTSL | |
| SCHEMBL7608833 | 0.74 | CTSL (0.43) | CTSLCTSSCTSKCTSB | |
| SCHEMBL23276791 | 0.74 | CTSL (0.39) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086099-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1086099-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | Aventis Pharmaceuticals Products Inc. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999062904-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-12-09 | — | — | WO | disclosed |