Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296693 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7378568 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL7289101 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7380817 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7298597 | 0.83 | GABRP (0.39) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7377706 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7291316 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7290034 | 0.82 | LMNA (0.38) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL9737761 | 0.81 | LMNA (0.38) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7374989 | 0.81 | ALDH1A1 (0.37) | ALDH1A1LMNAHPGDALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426018-B1 | Thiophene compounds and their pharmaceutical uses | YOSHITIOMI PHARMACEUTICAL IND (JP) | 1997-08-27 | — | — | EP | disclosed |
| EP-0729960-A1 | Thiophene compounds and their use as intermediates in the preparation of antianxiety drugs, hypnotics, antiepileptic drugs and nuotropics | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5329016-A | Antianxiety, hypnotic agents, antiepileptic agents or nootropics | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| US-5175162-A | Anxiolytic, antiepilepic agents | YOSHITIOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1992-12-29 | — | — | US | disclosed |