Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372627 | 0.82 | ENPP2 (0.49) | FFAR1FFAR4 | |
| SCHEMBL7375231 | 0.80 | — | — | |
| SCHEMBL9627231 | 0.79 | MAOB (0.74) | MAOBMAOAFFAR1 | |
| SCHEMBL3703276 | 0.78 | — | — | |
| SCHEMBL3509295 | 0.75 | MAOB (0.42) | MAOBMAOA | |
| SCHEMBL7377072 | 0.73 | TSHR (0.58) | MTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL11280610 | 0.71 | WDR5 (0.60) | MAOBMAOAPPARG | |
| SCHEMBL9626424 | 0.69 | MAOB (0.69) | MAOBMAOAFFAR1FFAR4 | |
| SCHEMBL11359239 | 0.69 | PTGDR2 (0.52) | — | |
| SCHEMBL11138297 | 0.69 | PTGDR2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380755-A | Monoamine oxidase inhibitors | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-10 | — | — | US | disclosed |