Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 3/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.33 |
| ▸ | IL1RN | P18510 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7405421 | 0.88 | CTSC (0.37) | MC4RMC3RCTSCSSTR4GHSR | |
| SCHEMBL7411057 | 0.88 | CTSC (0.37) | MC4RMC3RCTSCSSTR4GHSR | |
| SCHEMBL7360267 | 0.83 | CTSL (0.40) | CTSC | |
| SCHEMBL7414221 | 0.80 | CA2 (0.38) | CTSCSSTR4GHSR | |
| SCHEMBL7350474 | 0.80 | CTSL (0.44) | CTSC | |
| SCHEMBL8696045 | 0.80 | CA2 (0.38) | CTSCSSTR4GHSR | |
| SCHEMBL7354041 | 0.79 | CTSL (0.43) | CTSC | |
| SCHEMBL8159878 | 0.79 | CTSC (0.36) | CTSCSSTR4GHSR | |
| SCHEMBL7379877 | 0.78 | ACACB (0.42) | MC4RMC3R | |
| SCHEMBL7375700 | 0.78 | ERAP1 (0.33) | CTSCSSTR4GHSRERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |