Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 7/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696045 | 1.00 | CA2 (0.38) | CA2CA12CA1CTSCCTSB | |
| SCHEMBL8159878 | 0.90 | CTSC (0.36) | CA2CA12CA1CTSCCTSB | |
| SCHEMBL7355598 | 0.86 | CTSB (0.56) | CTSCCTSBCTSHCTSSCTSK | |
| SCHEMBL7349455 | 0.86 | CTSB (0.56) | CTSCCTSBCTSHCTSSCTSK | |
| SCHEMBL7411057 | 0.83 | CTSC (0.37) | CTSCSSTR4GHSR | |
| Hydrochloric Acid SCHEMBL7405421 | 0.83 | CTSC (0.37) | CTSCCTSBCTSHCTSSCTSK | |
| SCHEMBL7414186 | 0.83 | CTSC (0.33) | CA2CA12CA1CTSCCTSB | |
| SCHEMBL7352317 | 0.83 | CTSB (0.48) | CTSCCTSBCTSHCTSSCTSK | |
| SCHEMBL7350474 | 0.82 | CTSL (0.44) | CTSCCTSBCTSHCTSSCTSK | |
| SCHEMBL7410507 | 0.81 | CTSC (0.36) | CTSCSSTR4GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |