Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.54 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417458 | 0.90 | ITGA4 (0.49) | ITGB1ITGA4KMT2AALDH1A1HPGD | |
| SCHEMBL7588952 | 0.89 | ITGA4 (0.60) | ITGB1ITGA4WNT3ACHEK1MEN1 | |
| SCHEMBL7424464 | 0.87 | ITGB1 (0.56) | ITGB1ITGA4MEN1POLBMAPT | |
| SCHEMBL7391722 | 0.87 | ITGB1 (0.57) | ITGB1ITGA4WNT3API4KB | |
| SCHEMBL7425612 | 0.86 | ITGA4 (0.53) | ITGB1ITGA4WNT3ACHEK1 | |
| SCHEMBL7420868 | 0.85 | ITGA4 (0.61) | ITGB1ITGA4WNT3ACHEK1MEN1 | |
| SCHEMBL7476969 | 0.83 | ITGA4 (0.60) | ITGB1ITGA4WNT3ACHEK1MEN1 | |
| SCHEMBL7429626 | 0.83 | ITGB1 (0.59) | ITGB1ITGA4WNT3ACHEK1MEN1 | |
| SCHEMBL7429378 | 0.83 | ITGA4 (0.59) | ITGB1ITGA4WNT3ACHEK1MEN1 | |
| SCHEMBL7425600 | 0.83 | ITGA4 (0.52) | ITGB1ITGA4WNT3ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |