Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386056 | 0.90 | CTSG (0.52) | HDAC1HDAC6CTSGCMA1 | |
| SCHEMBL7390554 | 0.90 | CTSG (0.43) | HDAC1HDAC6KMT2ACTSGCMA1 | |
| SCHEMBL7385771 | 0.90 | HDAC1 (0.54) | HDAC1HDAC6KMT2ACTSGCMA1 | |
| SCHEMBL7386548 | 0.89 | ITGB3 (0.46) | HDAC1HDAC6KMT2ACTSGCMA1 | |
| SCHEMBL7388722 | 0.89 | HDAC1 (0.54) | HDAC1HDAC6CTSGCMA1 | |
| SCHEMBL7382682 | 0.88 | KMT2A (0.41) | HDAC1HDAC6KMT2ACTSGCMA1 | |
| SCHEMBL7384287 | 0.87 | CTSG (0.42) | HDAC1HDAC6KMT2ACTSGCMA1 | |
| SCHEMBL7386158 | 0.86 | ALDH1A1 (0.45) | HDAC1HDAC6CTSGCMA1ITGB3 | |
| SCHEMBL7388294 | 0.86 | TACR1 (0.46) | HDAC1HDAC6KMT2ACTSGCMA1 | |
| SCHEMBL7384580 | 0.86 | ALDH1A1 (0.46) | HDAC1HDAC6KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | claimed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | claimed |
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |