Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 6/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LYPLA1 | O75608 | 2/20 | 0.31 |
| ▸ | LYPLA2 | O95372 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15675036 | 0.92 | ALDH1A1 (0.43) | ALDH1A1TSHRDNM1KMT2ACA12 | |
| Hydrochloric Acid SCHEMBL7099693 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRDNM1KMT2ACA12 | |
| SCHEMBL489978 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6197073 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TSHRDNM1CA12CA2 | |
| SCHEMBL2263006 | 0.78 | APLNR (0.32) | — | |
| SCHEMBL14885530 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRDNM1THRBTHRA | |
| SCHEMBL14932176 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRDNM1THRBTHRA | |
| SCHEMBL353885 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRDNM1THRBTHRA | |
| SCHEMBL4107225 | 0.74 | FAAH (0.35) | CA2 | |
| SCHEMBL5903659 | 0.74 | FAAH (0.35) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |
| US-5010086-A | Enzyme inhibitor for treating congestive heart failure or hypertension in mammals | STERLING DRUG INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4963561-A | Phosphodiesterase inhibitors | STERLING DRUG INC. (US) | 1990-10-16 | — | — | US | disclosed |