Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664737 | 0.89 | ALDH1A1 (0.45) | EPHX2EPHX1HTR6GAAALDH1A1 | |
| SCHEMBL7383036 | 0.78 | CYP11B1 (0.49) | MAPTLMNACYP11B1MEN1KMT2A | |
| SCHEMBL16723452 | 0.76 | MAPT (0.43) | GAAMAPTCYP2C9KDM4EALDH1A1 | |
| SCHEMBL7385171 | 0.75 | EPHX2 (0.46) | EPHX2EPHX1HTR6GAAMAPT | |
| SCHEMBL7497164 | 0.75 | EPHX2 (0.46) | EPHX2EPHX1HTR6GAAMAPT | |
| SCHEMBL7497168 | 0.75 | EPHX2 (0.46) | EPHX2EPHX1HTR6GAAMAPT | |
| SCHEMBL25429745 | 0.74 | ALDH1A1 (0.48) | GAAMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL1292014 | 0.72 | ALDH1A1 (0.48) | GAAMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL17158242 | 0.71 | KCNN4 (0.50) | GAAMAPTCYP2C9KDM4EALDH1A1 | |
| SCHEMBL22578028 | 0.70 | ALDH1A1 (0.52) | GAAMAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000067-B1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-10-23 | — | — | EP | disclosed |
| EP-1000067-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005147-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1999-02-04 | — | — | WO | disclosed |