Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CCR9 | P51686 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | BRD1 | O95696 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 4/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226534 | 0.89 | L3MBTL1 (0.65) | L3MBTL1KDM4ETRPA1CYP11B2CYP11B1 | |
| SCHEMBL327634 | 0.85 | MAPT (0.51) | KDM4ECCR9BRPF1LMNATDP2 | |
| SCHEMBL326814 | 0.84 | MCL1 (0.57) | KDM4ETRPA1CCR9TDP2ALB | |
| SCHEMBL22369001 | 0.80 | CCR9 (0.45) | L3MBTL1KDM4ECCR9HTTTDP2 | |
| SCHEMBL3056564 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL7881270 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL30995153 | 0.78 | CYP11B2 (0.48) | L3MBTL1KDM4ECCR9CYP11B2CYP11B1 | |
| SCHEMBL2272634 | 0.78 | L3MBTL1 (0.80) | L3MBTL1KDM4ECCR9CYP11B2CYP11B1 | |
| SCHEMBL20618589 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL3924468 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5866577-A | AN ANTICOAGULANT AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |