Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995123 | 0.87 | MAPT (0.43) | CYP11B2KDM2BALDH1A1TSHRKDM4E | |
| SCHEMBL30995241 | 0.85 | CYP11B2 (0.48) | CYP11B2KDM2BALDH1A1TSHRKDM4E | |
| SCHEMBL30995134 | 0.82 | CYP11B2 (0.46) | CYP11B2TSHRKDM4ECYP11B1CCR9 | |
| SCHEMBL30995226 | 0.80 | CYP11B2 (0.53) | CYP11B2ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL7380299 | 0.78 | L3MBTL1 (0.54) | CYP11B2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL30995208 | 0.74 | CYP11B2 (0.40) | CYP11B2KDM2BALDH1A1TSHRKDM4E | |
| SCHEMBL30995193 | 0.74 | CYP11B2 (0.40) | CYP11B2KDM2BALDH1A1TSHRKDM4E | |
| SCHEMBL30995127 | 0.73 | HSD17B10 (0.41) | CYP11B2KDM2BALDH1A1TSHRKDM4E | |
| SCHEMBL20340205 | 0.73 | CYP11B2 (0.73) | CYP11B2CYP11B1 | |
| SCHEMBL21771755 | 0.71 | KDM2B (0.36) | CYP11B2KDM2BALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |