Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ITGAM | P11215 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379113 | 0.95 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2CASP1ATM | |
| SCHEMBL7373145 | 0.91 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2CASP1ATM | |
| SCHEMBL7668331 | 0.88 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2CASP1ATM | |
| SCHEMBL7378820 | 0.87 | MAPT (0.45) | RAB9ANPC1SMN1; SMN2CASP1L3MBTL1 | |
| SCHEMBL7670357 | 0.86 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2CASP1ATM | |
| SCHEMBL7528476 | 0.85 | MAPT (0.44) | RAB9ANPC1SMN1; SMN2CASP1L3MBTL1 | |
| SCHEMBL7381323 | 0.85 | LMNA (0.48) | RAB9ANPC1SMN1; SMN2CASP1L3MBTL1 | |
| SCHEMBL7371099 | 0.82 | ITGB3 (0.55) | RAB9ANPC1SMN1; SMN2CASP1ATM | |
| SCHEMBL7375423 | 0.81 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2CASP1ATM | |
| SCHEMBL7667816 | 0.80 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2CASP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131320-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-09-12 | — | — | EP | claimed |
| WO-2000029407-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-05-25 | — | — | WO | claimed |
| EP-1131320-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029407-A1 | ISOXAZOLINE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |