Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27336449 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6216370 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL27635816 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MAPTRAB9AKMT2ANPC1 | |
| SCHEMBL10754839 | 0.82 | CYP1A2 (0.39) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11668532 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL10755050 | 0.81 | RAB9A (0.39) | ALDH1A1MAPTRAB9AKMT2ANPC1 | |
| SCHEMBL1000856 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL4611278 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL10591403 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11102564 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101362735-B | Preparation method of ethyl 2-[[(bezyloxy)carbonyl]amido]-4-thiazolyl acetate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICALS CO LTD | 2011-01-05 | — | — | CN | claimed |
| CN-101541811-B | Pyrazolopyrimidine Derivatives | DAIICHI SANKYO CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-101130526-B | Aryl carbonyl derivatives as therapeutic agents | NOVO NORDISK AS | 2013-07-10 | — | — | CN | disclosed |
| CN-101362735-B | Preparation method of ethyl 2-[[(bezyloxy)carbonyl]amido]-4-thiazolyl acetate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICALS CO LTD | 2011-01-05 | — | — | CN | disclosed |
| CN-101925300-A | Novel compounds as cannabinoid receptor ligands and uses thereof | ABBOTT LAB | 2010-12-22 | — | — | CN | disclosed |
| CN-101541811-A | Pyrazolopyrimidine Derivatives | DAIICHI SANKYO CO LTD (JP) | 2009-09-23 | — | — | CN | disclosed |
| CN-101454302-A | Thiazole compounds as cannabinoid receptor ligands and uses thereof | ABBOTT LAB (US) | 2009-06-10 | — | — | CN | disclosed |
| CN-101362735-A | Preparation method of ethyl 2-[[(bezyloxy)carbonyl]amido]-4-thiazolyl acetate | SHANDONG JINCHENG PHARMACEUTIC (CN) | 2009-02-11 | — | — | CN | disclosed |
| CN-101316836-A | Substituted dihydroisoindolones as allosteric modulators of glucokinase | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-03 | — | — | CN | disclosed |
| CN-100384856-C | Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity | MERCK & CO INC (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-1249039-C | Inhibitors of 11 beta-hydroxysteroid dehydrogenase type I | BIOVITRUM AB (SE) | 2006-04-05 | — | — | CN | disclosed |
| CN-1678311-A | Arylcarbonyl derivatives useful as therapeutic agents | NOVO NORDISK AS (DK) | 2005-10-05 | — | — | CN | disclosed |
| CN-1543459-A | Quinoline derivative and quinazoline derivative having azolyl group | ������������ʽ���� | 2004-11-03 | — | — | CN | disclosed |
| CN-1438997-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type I | BIOVITRUM AB (SE) | 2003-08-27 | — | — | CN | disclosed |
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0880511-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-06-16 | — | — | EP | disclosed |
| EP-0880511-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026250-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-07-24 | — | — | WO | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |