Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | HTR1D | P28221 | 1/20 | 0.65 |
| ▸ | HTR1B | P28222 | 1/20 | 0.65 |
| ▸ | HTR1F | P30939 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033159 | 0.86 | HTR6 (0.80) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL2204865 | 0.84 | HTR6 (0.76) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL5268569 | 0.82 | HTR6 (0.70) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL8412387 | 0.81 | HTR6 (0.65) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL9094606 | 0.81 | HTR6 (0.73) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL1486947 | 0.81 | HTR6 (1.00) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL3029129 | 0.81 | HTR6 (0.75) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL2204353 | 0.80 | HTR6 (0.74) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL7381366 | 0.80 | HTR6 (0.74) | HTR6HTR1ADRD2DRD4HTR1D | |
| Hydrochloric Acid SCHEMBL1486945 | 0.80 | HTR6 (0.97) | HTR6HTR1ADRD2DRD4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994477-A | Hypotensive agents | ABBOTT LABORATORIES (US) | 1991-02-19 | — | — | US | disclosed |