Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PKLR | P30613 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | HTR1D | P28221 | 2/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16366296 | 1.00 | PTPRA (0.73) | PTPRACYP2C19PKMPKLRHTR2A | |
| SCHEMBL27717137 | 0.90 | HTR2A (0.60) | PTPRACYP2C19PKMPKLRHTR2A | |
| SCHEMBL2965137 | 0.84 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRHTR2A | |
| SCHEMBL145392 | 0.84 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRHTR2A | |
| SCHEMBL30381729 | 0.84 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRHTR2A | |
| SCHEMBL3519524 | 0.84 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRHTR2A | |
| SCHEMBL30789181 | 0.84 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRHTR2A | |
| SCHEMBL10265469 | 0.84 | PKM (0.69) | PTPRACYP2C19PKMPKLRALDH1A1 | |
| SCHEMBL20931031 | 0.83 | PTPRA (0.75) | PTPRACYP2C19PKMPKLRBLM | |
| SCHEMBL22288108 | 0.83 | PTPRA (0.75) | PTPRACYP2C19PKMPKLRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020155017-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2020-08-06 | — | — | WO | disclosed |