Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577373 | 0.86 | LMNA (0.63) | MEN1KMT2ALMNAALDH1A1RECQL | |
| SCHEMBL7823860 | 0.86 | MEN1 (0.70) | MEN1KMT2ALMNAALDH1A1RECQL | |
| SCHEMBL9843646 | 0.84 | LMNA (0.66) | MEN1KMT2ALMNAALDH1A1RECQL | |
| SCHEMBL5182303 | 0.83 | LMNA (0.69) | MEN1KMT2ALMNAALDH1A1RECQL | |
| SCHEMBL6769086 | 0.80 | LMNA (0.64) | MEN1KMT2ALMNAALDH1A1RECQL | |
| SCHEMBL6593159 | 0.80 | LMNA (0.68) | MEN1KMT2ALMNAALDH1A1RECQL | |
| SCHEMBL16322460 | 0.78 | MEN1 (0.61) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8133836 | 0.77 | MEN1 (0.60) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL3792013 | 0.76 | LMNA (0.64) | MEN1KMT2ALMNAALDH1A1RECQL | |
| SCHEMBL15562567 | 0.76 | LMNA (0.64) | MEN1KMT2ALMNAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000050419-A1 | SUBSTITUTED BICYCLIC HETEROCYCLES AND THE USE THEREOF AS THROMBIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-08-31 | — | — | WO | disclosed |