Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAC1 | P63000 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666829 | 0.88 | ALDH1A1 (0.52) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL6769086 | 0.87 | LMNA (0.64) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL6593159 | 0.87 | LMNA (0.68) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL5182303 | 0.84 | LMNA (0.69) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL7380747 | 0.84 | MEN1 (0.65) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL8876963 | 0.84 | KMT2A (0.63) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL3792013 | 0.83 | LMNA (0.64) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL15562567 | 0.83 | LMNA (0.64) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL2853072 | 0.83 | LMNA (0.73) | LMNAMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL2853073 | 0.83 | LMNA (0.73) | LMNAMEN1KMT2AALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413832-A1 | OXAZOLIDINEDIONE DERIVATIVES AND PRODUCTION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-02-27 | — | — | EP | disclosed |