Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RAC1 | P63000 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182303 | 0.89 | LMNA (0.69) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL9843646 | 0.87 | LMNA (0.66) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL6769086 | 0.85 | LMNA (0.64) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL15562788 | 0.85 | LMNA (0.58) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL15562567 | 0.85 | LMNA (0.64) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL3792013 | 0.85 | LMNA (0.64) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL11577373 | 0.84 | LMNA (0.63) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL10937894 | 0.84 | RAB9A (0.64) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL584346 | 0.83 | ALDH1A1 (0.73) | LMNARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL2853073 | 0.81 | LMNA (0.73) | LMNARECQLKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013024427-A1 | NOVEL UREA DERIVATIVES AS TEC KINASE INHIBITORS AND USES THEREOF | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-02-21 | — | — | WO | disclosed |
| EP-1156044-B1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6562839-B1 | Effective for the therapy of disorder of cerebral nerve cells as antagonists against excitatory amino acid receptors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1156044-A1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |