Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170083 | 0.81 | HSD17B10 (0.56) | KDM4ELMNASMN1; SMN2PKMGAA | |
| SCHEMBL9587954 | 0.81 | SMN1; SMN2 (0.50) | KDM4ELMNASMN1; SMN2PKMGAA | |
| SCHEMBL3020581 | 0.79 | KDM4E (0.58) | KDM4ELMNACTSVCTSLGAA | |
| SCHEMBL6715526 | 0.78 | MTNR1A (0.60) | KDM4ELMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL7380843 | 0.78 | KDM4E (0.54) | KDM4ESMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL3943238 | 0.78 | KDM4E (0.55) | KDM4ELMNACTSVCTSLGAA | |
| SCHEMBL9181116 | 0.78 | CTSV (0.60) | KDM4ELMNASMN1; SMN2CTSVCTSL | |
| SCHEMBL5565082 | 0.77 | KDM4E (0.62) | KDM4ELMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL31437284 | 0.77 | KDM4E (0.62) | KDM4ELMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL4764681 | 0.77 | CTSV (0.67) | KDM4ELMNASMN1; SMN2CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015179-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |