Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977600 | 1.00 | CRBN (0.37) | CRBNKMT2AMAPK1ALDH1A1CTSK | |
| SCHEMBL10660255 | 0.73 | — | — | |
| SCHEMBL6963835 | 0.73 | — | — | |
| SCHEMBL6963830 | 0.73 | — | — | |
| SCHEMBL6975819 | 0.72 | KMT2A (0.37) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6975816 | 0.72 | KMT2A (0.37) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5156976 | 0.71 | BRD4 (0.34) | — | |
| SCHEMBL4098581 | 0.71 | BRD4 (0.34) | — | |
| SCHEMBL7387880 | 0.70 | TSHR (0.39) | KMT2AALDH1A1 | |
| SCHEMBL6970938 | 0.70 | KMT2A (0.42) | CRBNKMT2AMAPK1ALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018073-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-04-15 | — | — | WO | disclosed |