Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379492 | 0.92 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3SIGMAR1MEN1 | |
| SCHEMBL7382542 | 0.92 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3GRIN2DGRIN3B | |
| SCHEMBL7379363 | 0.92 | SIGMAR1 (0.42) | SLC6A2SLC6A4SLC6A3GRIN2DGRIN3B | |
| SCHEMBL7381688 | 0.86 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3SIGMAR1MEN1 | |
| SCHEMBL7381144 | 0.85 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL7380458 | 0.82 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3SIGMAR1MEN1 | |
| Hydrochloric Acid SCHEMBL7381355 | 0.80 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7383831 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL7374018 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3SIGMAR1MEN1 | |
| SCHEMBL7384166 | 0.77 | HTR1A (0.38) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137911-A | ISOCHROMANE DERIVATIVES | AKZO N.V. (NL) | 1992-08-11 | — | — | US | disclosed |
| EP-0450689-A1 | New isochromane derivatives | Akzo Nobel N.V. (NL) | 1991-10-09 | — | — | EP | disclosed |