Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379492 | 0.85 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7294243 | 0.85 | SIGMAR1 (0.43) | SLC6A4SLC6A3 | |
| SCHEMBL7380458 | 0.83 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7381355 | 0.81 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7382808 | 0.77 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7322676 | 0.76 | KCNH2 (0.42) | KMT2A | |
| SCHEMBL7382542 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7292958 | 0.76 | KCNH2 (0.38) | SLC6A4SLC6A3KMT2A | |
| SCHEMBL7381688 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7379363 | 0.76 | SIGMAR1 (0.42) | HTR1AADRA1DADRA1AADRA1BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137911-A | ISOCHROMANE DERIVATIVES | AKZO N.V. (NL) | 1992-08-11 | — | — | US | disclosed |
| EP-0450689-A1 | New isochromane derivatives | Akzo Nobel N.V. (NL) | 1991-10-09 | — | — | EP | disclosed |