Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082018 | 0.92 | HTR1A (0.48) | HTR1A | |
| SCHEMBL7356374 | 0.90 | HTR1A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL7355825 | 0.90 | MPO (0.48) | HTR1ASLC6A4 | |
| SCHEMBL7350360 | 0.90 | ADRA2A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL7352278 | 0.90 | BCHE (0.47) | HTR1AACHESLC6A4 | |
| SCHEMBL7356533 | 0.90 | ADRA2A (0.46) | HTR1ASLC6A4 | |
| SCHEMBL7881273 | 0.86 | HTR1A (0.53) | HTR1AACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7075871 | 0.86 | HTR1A (0.43) | HTR1A | |
| SCHEMBL6954494 | 0.84 | SLC6A4 (0.61) | HTR1AACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6954897 | 0.84 | SLC6A4 (0.61) | HTR1AACHESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GmbH (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |