Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383064 | 0.91 | FPR2 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7383128 | 0.85 | MAPT (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7382435 | 0.84 | RAB9A (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7376225 | 0.83 | MAPT (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7384102 | 0.83 | MAPT (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7383783 | 0.83 | SMN1; SMN2 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7384793 | 0.82 | SMN1; SMN2 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7386048 | 0.82 | FPR2 (0.48) | MEN1KMT2ASMN1; SMN2RAB9AGAA | |
| SCHEMBL7370619 | 0.81 | RAB9A (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7379939 | 0.79 | MAPT (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |