Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385158 | 0.83 | HSD17B10 (0.43) | TP53DDB1CRBNCYP1A2CYP3A4 | |
| SCHEMBL7384136 | 0.80 | MEN1 (0.44) | POLBMAPK1 | |
| SCHEMBL7381326 | 0.80 | MEN1 (0.44) | POLBMAPK1 | |
| SCHEMBL7387268 | 0.80 | GPBAR1 (0.39) | DDB1CRBNCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7388484 | 0.74 | HTT (0.41) | TP53MAPK1 | |
| SCHEMBL7385425 | 0.74 | KCNQ2 (0.39) | CYP1A2TSHRCYP2C19POLB | |
| SCHEMBL7381276 | 0.73 | GAA (0.42) | DDB1CRBNTSHR | |
| SCHEMBL7387023 | 0.72 | KCNQ2 (0.45) | DDB1CRBNPOLB | |
| SCHEMBL4382787 | 0.72 | KDM4E (0.34) | TP53CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7377871 | 0.71 | PTGS1 (0.40) | CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| WO-1999024395-A1 | COMPOUNDS WHICH INHIBIT TRYPTASE ACTIVITY | ARRAY BIOPHARMA, INC. (US) | 1999-05-20 | — | — | WO | disclosed |