Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381326 | 0.83 | MEN1 (0.44) | GAAALDH1A1LMNAMAPK1POLB | |
| SCHEMBL7384136 | 0.83 | MEN1 (0.44) | GAAALDH1A1LMNAMAPK1POLB | |
| SCHEMBL7379863 | 0.83 | MEN1 (0.44) | GAAALDH1A1LMNAMAPK1POLB | |
| SCHEMBL7468058 | 0.81 | LMNA (0.37) | HSD17B10TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7384543 | 0.80 | MTNR1A (0.40) | TP53DDB1CRBN | |
| SCHEMBL7381276 | 0.80 | GAA (0.42) | TSHRGAADDB1CRBNMAPT | |
| SCHEMBL7387023 | 0.79 | KCNQ2 (0.45) | DDB1CRBNPOLBL3MBTL1KDM4E | |
| SCHEMBL7383592 | 0.76 | CHRM2 (0.39) | TSHRCYP1A2CYP2C19DDB1CRBN | |
| SCHEMBL7385425 | 0.76 | KCNQ2 (0.39) | TSHRCYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL7378937 | 0.74 | KCNQ2 (0.40) | HSD17B10TSHRCYP1A2CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |