Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381077 | 0.84 | ACE (0.45) | TAS1R3TAS1R1 | |
| SCHEMBL8486193 | 0.81 | HRH4 (0.45) | MME | |
| SCHEMBL8486197 | 0.81 | HRH4 (0.45) | MME | |
| SCHEMBL7386107 | 0.80 | SMN1; SMN2 (0.39) | HDAC6 | |
| SCHEMBL7380910 | 0.80 | KMT2A (0.45) | GAAHDAC6 | |
| SCHEMBL9875926 | 0.78 | ALDH1A1 (0.53) | GAA | |
| SCHEMBL9875934 | 0.78 | ALDH1A1 (0.53) | GAA | |
| SCHEMBL23792241 | 0.73 | MGAM (0.42) | TAS1R3TAS1R1MT-CO2MGAMAMY1A | |
| SCHEMBL5808669 | 0.72 | HDAC6 (0.39) | GAAHDAC6 | |
| SCHEMBL5808668 | 0.72 | HDAC6 (0.39) | GAAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870183-A | RENIN INHIBITORS, HYPOTENSIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0252727-A1 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-01-13 | — | — | EP | disclosed |