Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384389 | 0.84 | TAS1R3 (0.36) | TAS1R3TAS1R1 | |
| SCHEMBL9875926 | 0.80 | ALDH1A1 (0.53) | HSD17B10 | |
| SCHEMBL9875934 | 0.80 | ALDH1A1 (0.53) | HSD17B10 | |
| SCHEMBL7380910 | 0.75 | KMT2A (0.45) | CYP3A4HSD17B10 | |
| SCHEMBL7386107 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10 | |
| SCHEMBL8486193 | 0.73 | HRH4 (0.45) | ACEHRH4MMP2MMP9MMP8 | |
| SCHEMBL8486197 | 0.73 | HRH4 (0.45) | ACEHRH4MMP2MMP9MMP8 | |
| SCHEMBL25987895 | 0.73 | TAAR1 (0.59) | SMN1; SMN2TAS1R3TAS1R1CYP3A4HPGD | |
| SCHEMBL5808669 | 0.73 | HDAC6 (0.39) | HSD17B10 | |
| SCHEMBL7118271 | 0.73 | TAAR1 (0.58) | SMN1; SMN2TAS1R3TAS1R1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870183-A | RENIN INHIBITORS, HYPOTENSIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0252727-A1 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-01-13 | — | — | EP | disclosed |