Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380910 | 0.87 | KMT2A (0.45) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL8486193 | 0.85 | HRH4 (0.45) | — | |
| SCHEMBL8486197 | 0.85 | HRH4 (0.45) | — | |
| SCHEMBL9875934 | 0.84 | ALDH1A1 (0.53) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9875926 | 0.84 | ALDH1A1 (0.53) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7384389 | 0.80 | TAS1R3 (0.36) | HDAC6 | |
| SCHEMBL7386111 | 0.80 | REN (0.48) | — | |
| SCHEMBL7056934 | 0.78 | MAPT (0.36) | SMN1; SMN2TP53MAPTALDH1A1THRB | |
| SCHEMBL10436048 | 0.77 | OPRK1 (0.55) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9551271 | 0.77 | ALDH1A1 (0.53) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870183-A | RENIN INHIBITORS, HYPOTENSIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0252727-A1 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-01-13 | — | — | EP | disclosed |