Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 8/20 | 0.35 |
| ▸ | DRD3 | P35462 | 5/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910493 | 0.87 | DRD2 (0.37) | KDM1ADRD2DRD3SCN9ATSHR | |
| SCHEMBL7385405 | 0.79 | DRD2 (0.41) | KDM1ADRD2DRD3SCN9ATSHR | |
| SCHEMBL7384873 | 0.79 | DRD2 (0.41) | KDM1ADRD2DRD3SCN9ATSHR | |
| SCHEMBL7384878 | 0.79 | DRD2 (0.41) | KDM1ADRD2DRD3SCN9ATSHR | |
| SCHEMBL7392978 | 0.77 | DRD2 (0.36) | KDM1ADRD2DRD3SCN9ATSHR | |
| SCHEMBL7392980 | 0.77 | DRD2 (0.36) | KDM1ADRD2DRD3SCN9ATSHR | |
| SCHEMBL8574886 | 0.75 | ALDH1A1 (0.41) | KMT2A | |
| SCHEMBL8911497 | 0.74 | PSMB5 (0.38) | NPC1RAB9A | |
| SCHEMBL8576519 | 0.72 | PSMB5 (0.42) | RAB9AMEN1KMT2A | |
| SCHEMBL8911184 | 0.72 | RORC (0.40) | RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |