Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.64 |
| ▸ | ACE | P12821 | 3/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10949495 | 0.99 | MME (0.62) | MMEACENAALAD2MMEL1 | |
| SCHEMBL650610 | 0.91 | ACE (0.59) | MMEACENAALAD2MMEL1 | |
| SCHEMBL5603448 | 0.91 | ACE (0.59) | MMEACENAALAD2MMEL1 | |
| SCHEMBL391211 | 0.91 | ACE (0.59) | MMEACENAALAD2MMEL1 | |
| SCHEMBL10943595 | 0.87 | HRH4 (0.50) | MMEACE | |
| SCHEMBL7380315 | 0.86 | MMEL1 (0.64) | MMEACEMMEL1 | |
| SCHEMBL7385743 | 0.86 | MMEL1 (0.64) | MMEACEMMEL1 | |
| SCHEMBL5870198 | 0.83 | MME (0.88) | MMEACENAALAD2 | |
| SCHEMBL8258027 | 0.83 | MME (0.88) | MMEACENAALAD2 | |
| SCHEMBL11296564 | 0.83 | ATM (0.52) | MMEACENAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906615-A | Substituted dipeptides as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4721726-A | ANALGESICS | SCHERING CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |