Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.64 |
| ▸ | MME | P08473 | 4/20 | 0.61 |
| ▸ | ACE | P12821 | 3/20 | 0.54 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380315 | 1.00 | MMEL1 (0.64) | MMEL1MMEACECPA1ACE2 | |
| SCHEMBL5603448 | 0.95 | ACE (0.59) | MMEL1MMEACE | |
| SCHEMBL391211 | 0.95 | ACE (0.59) | MMEL1MMEACE | |
| SCHEMBL650610 | 0.95 | ACE (0.59) | MMEL1MMEACE | |
| SCHEMBL11296564 | 0.86 | ATM (0.52) | MMEACE | |
| SCHEMBL7385019 | 0.86 | MME (0.64) | MMEL1MMEACE | |
| SCHEMBL7383477 | 0.86 | MME (0.54) | MMEL1MMEACECPA1ACE2 | |
| Water SCHEMBL10949495 | 0.85 | MME (0.62) | MMEL1MMEACE | |
| SCHEMBL10651220 | 0.85 | MMEL1 (0.56) | MMEL1MMEACE | |
| SCHEMBL7387218 | 0.84 | MME (0.82) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103077-B1 | SUBSTITUTED DIPEPTIDES, METHODS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, METHOD FOR MAKING SUCH PHARMACEUTICAL COMPOSITIONS | SCHERING CORPORATION (US) | 1988-05-18 | — | — | EP | claimed |
| US-4906615-A | Substituted dipeptides as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4721726-A | ANALGESICS | SCHERING CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |