Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430372 | 0.84 | ACP3 (0.50) | ACP3CYP2C19KMT2AMEN1MEP1B | |
| SCHEMBL9427609 | 0.84 | ACP3 (0.50) | ACP3CYP2C19KMT2AMEN1MEP1B | |
| SCHEMBL14099897 | 0.82 | ACP3 (0.53) | ACP3CYP3A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1305451 | 0.82 | ACP3 (0.53) | ACP3CYP3A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7189369 | 0.82 | ACP3 (0.53) | ACP3CYP3A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19248981 | 0.78 | MEN1 (0.59) | ACP3KMT2AMEN1MEP1BSMN1; SMN2 | |
| SCHEMBL1696017 | 0.78 | MEN1 (0.59) | ACP3KMT2AMEN1MEP1BSMN1; SMN2 | |
| SCHEMBL13191170 | 0.78 | AOC3 (0.55) | ACP3CYP3A4CYP2C19KMT2AMEN1 | |
| SCHEMBL5269591 | 0.78 | AOC3 (0.55) | ACP3CYP3A4CYP2C19KMT2AMEN1 | |
| SCHEMBL27827175 | 0.78 | MEN1 (0.59) | ACP3KMT2AMEN1MEP1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208240-A | Alzeheimer's, cardiovascular, respiratory | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0503563-A2 | Novel 8-substituted purines as selective adenosine receptor agents | MERRELL PHARMACEUTICALS INC. (US) | 1992-09-16 | — | — | EP | disclosed |