Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ACP3 | P15309 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.47 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191170 | 1.00 | AOC3 (0.55) | AOC3ALDH1A1LMNAMAPK1HTT | |
| SCHEMBL5268676 | 0.90 | SMN1; SMN2 (0.54) | AOC3ALDH1A1LMNAMAPK1HTT | |
| SCHEMBL5273602 | 0.90 | CYP1A2 (0.62) | AOC3ALDH1A1LMNAMAPK1HTT | |
| SCHEMBL5274497 | 0.86 | TDP1 (0.56) | ALDH1A1LMNAMAPK1HTTNPSR1 | |
| SCHEMBL1305451 | 0.86 | ACP3 (0.53) | ALDH1A1LMNAMAPK1HTTNPSR1 | |
| SCHEMBL7189369 | 0.86 | ACP3 (0.53) | ALDH1A1LMNAMAPK1HTTNPSR1 | |
| SCHEMBL14099897 | 0.86 | ACP3 (0.53) | ALDH1A1LMNAMAPK1HTTNPSR1 | |
| SCHEMBL17314012 | 0.83 | SIGMAR1 (0.52) | ALDH1A1LMNAMAPK1HTTNPSR1 | |
| SCHEMBL8430372 | 0.80 | ACP3 (0.50) | ALDH1A1LMNAMAPK1HTTNPSR1 | |
| SCHEMBL9427609 | 0.80 | ACP3 (0.50) | ALDH1A1LMNAMAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094281-B | Chemical process for preparing monolactam antibiotics and intermediates thereof | 诺华股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-11414411-B2 | Chemical process for manufacturing monobactam antibiotic and intermediates thereof | NOVARTIS AG (CH) | 2022-08-16 | — | — | US | disclosed |
| EP-3661933-B1 | PROCESS FOR PREPARING 1-(((Z)-(1-(2-AMINOTHIAZOL-4-YL)-2-OXO-2-(((3S,4R)-2-OXO-4-((2-OXOOXAZOLIDIN-3-YL)METHYL)-1-SULFOAZETIDIN-3- YL)AMINO)ETHYLIDENE)AMINO)OXY)CYCLOPROPANE CARBOXYLIC ACID | NOVARTIS AG (CH) | 2022-03-23 | — | — | EP | disclosed |
| US-20200239461-A1 | CHEMICAL PROCESS FOR MANUFACTURING MONOBACTAM ANTIBIOTIC AND INTERMEDIATES THEREOF | SUZHOU NOVARTIS PHARMA TECHNOLOGY CO., LTD. (CN) | 2020-07-30 | — | — | US | disclosed |
| CN-111094281-A | Chemical process for the preparation of monobactam antibiotics and intermediates thereof | 诺华股份有限公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-1074539-B1 | Process for producing optically active 3,3,3,-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL CO (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-6894190-B2 | Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-17 | — | — | US | disclosed |
| US-20030232886-A1 | Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-12-18 | — | — | US | disclosed |
| US-6653507-B2 | Useful intermediate compound of pharmaceuticals for urinary incontinence | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-11-25 | — | — | US | disclosed |
| US-20020143212-A1 | Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-10-03 | — | — | US | disclosed |
| US-6403832-B1 | MIXING ACID WITH AMINE, PRECIPITATING SALT, AND FILTERING; GOOD OPTICAL PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1074539-A2 | Process for producing optically active 3,3,3,-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414411-B2 | Chemical process for manufacturing monobactam antibiotic and intermediates thereof | SRR, DCXR, JMJD6 | AOC3 1835/4885ALDH1A1 3899/4885LMNA 4393/4885 |
| US-20030232886-A1 | Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | ALDH1A2, CYP8B1, CYP11B2 | AOC3 483/4885ALDH1A1 141/4885LMNA 1166/4885 |
| US-20200239461-A1 | CHEMICAL PROCESS FOR MANUFACTURING MONOBACTAM ANTIBIOTIC AND INTERMEDIATES THEREOF | SRR, DCXR, JMJD6 | AOC3 1835/4885ALDH1A1 3899/4885LMNA 4393/4885 |
| US-20020143212-A1 | Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | ALDH1A2, ALDH7A1, ALDH18A1 | AOC3 169/4885ALDH1A1 73/4885LMNA 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.