Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427609 | 1.00 | ACP3 (0.50) | ACP3GABRB1GABRB2CYP1A2CYP2D6 | |
| SCHEMBL7385115 | 0.84 | ACP3 (0.51) | ACP3GABRB1GABRB2CYP1A2CYP2C19 | |
| SCHEMBL2491875 | 0.84 | KMT2A (0.57) | ACP3CYP2C19MEN1KMT2ALMNA | |
| SCHEMBL1305451 | 0.81 | ACP3 (0.53) | ACP3MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14099897 | 0.81 | ACP3 (0.53) | ACP3MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7189369 | 0.81 | ACP3 (0.53) | ACP3MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL5269591 | 0.80 | AOC3 (0.55) | ACP3CYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL13191170 | 0.80 | AOC3 (0.55) | ACP3CYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL17314012 | 0.79 | SIGMAR1 (0.52) | ACP3CYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL6462875 | 0.79 | GABRB1 (0.51) | ACP3GABRB1GABRB2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939561-A | Process for the preparation of β-phenylisoserine and β-lactam and their analogues | RHONE-POULENCE RORER S.A. (FR) | 1999-08-17 | — | — | US | disclosed |
| EP-0630365-B1 | METHOD FOR PREPARING BETA-PHENYLISOSERINE AND ANALOGUES THEREOF | RHONE POULENC RORER SA (FR) | 1997-10-22 | — | — | EP | disclosed |
| US-5608102-A | Process for the preparation of β-phenylisoserine and its analogues | RHONE-POULENC RORER S.A. (FR) | 1997-03-04 | — | — | US | disclosed |