Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11732915 | 0.77 | HTR2A (0.50) | ANPEPHTR2AHDAC4HDAC7HDAC5 | |
| SCHEMBL20148794 | 0.73 | HTR2A (0.56) | ANPEPHTR2AHDAC4HDAC7HDAC5 | |
| SCHEMBL9853855 | 0.71 | CYP1A2 (0.38) | KMT2ATSHRALDH1A1CYP3A4LMNA | |
| SCHEMBL1207850 | 0.71 | HDAC4 (0.51) | ANPEPHTR2AHDAC4HDAC7HDAC5 | |
| SCHEMBL10739890 | 0.70 | ACP3 (0.47) | HTR2AKMT2ATSHRMTNR1BNPSR1 | |
| SCHEMBL11967586 | 0.67 | HTR2A (0.53) | ANPEPHTR2AHDAC4HDAC7HDAC5 | |
| SCHEMBL6045078 | 0.66 | ANPEP (0.53) | ANPEPHTR2AHDAC4HDAC7HDAC5 | |
| SCHEMBL7397320 | 0.66 | SLC6A3 (0.40) | KMT2ATSHRALDH1A1KDM1ALMNA | |
| SCHEMBL29229994 | 0.65 | ESR1 (0.49) | TSHRALDH1A1LMNAMTNR1BUSP2 | |
| SCHEMBL5794548 | 0.65 | ANPEP (0.47) | ANPEPHTR2AKMT2AHDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194400-A1 | 2-AMINOINDANE ANALOGS | Prescient Neuropharma Inc. (CA) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001002342-A1 | 2-AMINOINDANE ANALOGS | IGT PHARMA INC. (CA) | 2001-01-11 | — | — | WO | disclosed |