Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347693 | 0.79 | — | — | |
| SCHEMBL7390519 | 0.78 | — | — | |
| SCHEMBL5757984 | 0.74 | NPC1 (0.32) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL159256 | 0.70 | KDM4E (0.42) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL182637 | 0.70 | HTR1A (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15474677 | 0.70 | SYK (0.51) | — | |
| SCHEMBL29193650 | 0.69 | APP (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8674 | 0.69 | CA2 (0.46) | ALDH1A1 | |
| SCHEMBL29193639 | 0.69 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7383133 | 0.69 | SMN1; SMN2 (0.33) | NPC1RAB9ASMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389620-A | Bronchodilation agent, vasodilation | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |