Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481020 | 0.91 | RAB9A (0.52) | KMT2ASMN1; SMN2RAB9ANPC1ITGB1 | |
| SCHEMBL7391216 | 0.87 | ITGB1 (0.45) | KMT2AITGB1ITGA4OPRM1MEN1 | |
| SCHEMBL7485087 | 0.82 | ITGB1 (0.44) | KMT2ASMN1; SMN2RAB9ANPC1ITGB1 | |
| SCHEMBL7424847 | 0.81 | ITGB1 (0.46) | KMT2AITGB1ITGA4OPRM1MEN1 | |
| SCHEMBL7390416 | 0.78 | ITGA4 (0.52) | KMT2ASMN1; SMN2ITGB1ITGA4CHRM2 | |
| SCHEMBL7387024 | 0.74 | ITGB1 (0.46) | KMT2ASMN1; SMN2ITGB1ITGA4MEN1 | |
| SCHEMBL7391866 | 0.74 | ITGA4 (0.45) | KMT2AITGB1ITGA4MEN1MAPT | |
| SCHEMBL7429192 | 0.74 | ITGB1 (0.53) | KMT2ASMN1; SMN2RAB9ANPC1ITGB1 | |
| SCHEMBL7428617 | 0.73 | OPRM1 (0.49) | ITGB1ITGA4CHRM3OPRM1 | |
| SCHEMBL7430185 | 0.71 | ITGB1 (0.45) | KMT2AITGB1ITGA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |