Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 9/20 | 0.43 |
| ▸ | PYGM | P11217 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383535 | 0.93 | CYP2C9 (0.48) | ALOX15ACHENR3C2PYGLPYGM | |
| SCHEMBL7384908 | 0.90 | CYP2C9 (0.43) | ALOX15ACHENR3C2PYGLPYGM | |
| SCHEMBL7382716 | 0.90 | ALOX15 (0.50) | ALOX15ACHENR3C2PYGLPYGM | |
| SCHEMBL7377019 | 0.89 | KDM4E (0.50) | MAPTKDM4ETDP1CYP1A2CYP3A4 | |
| SCHEMBL7385349 | 0.87 | KDM4E (0.54) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7382382 | 0.86 | NR3C2 (0.45) | ALOX15NR3C2MAPTKDM4ECYP1A2 | |
| SCHEMBL7376680 | 0.84 | TBXA2R (0.48) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7385182 | 0.84 | CYP2C9 (0.49) | ALOX15NR3C2MAPTKDM4ECYP1A2 | |
| SCHEMBL7376670 | 0.82 | ALDH1A1 (0.51) | MAPTKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7384438 | 0.82 | CYP2C9 (0.46) | ALOX15MAPTKDM4ETDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889866-A | CARDIOVASCULAR DISEASES, HYPOTENSIVE AGENTS, CONGESTIVE HEART FAILURE | SYNTEX (U.S.A.) INC. (US) | 1989-12-26 | — | — | US | disclosed |