Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945373 | 0.65 | NQO1 (0.55) | MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6953448 | 0.64 | RXRA (0.34) | ALDH1A1CYP3A4MAPTTSHRTDP1 | |
| SCHEMBL8383568 | 0.57 | MAPT (0.51) | MEN1USP2ALDH1A1HPNCYP3A4 | |
| SCHEMBL8383583 | 0.54 | MEN1 (0.47) | MEN1USP2ALDH1A1HPNCYP3A4 | |
| SCHEMBL7388345 | 0.54 | CREB1 (0.39) | MEN1ALDH1A1MAPTTHRBKMT2A | |
| SCHEMBL7387195 | 0.54 | ACHE (0.36) | MEN1ALDH1A1MAPTTHRBKMT2A | |
| SCHEMBL7349571 | 0.54 | NQO1 (0.42) | ALDH1A1TSHRKMT2ATDP1L3MBTL1 | |
| SCHEMBL7358536 | 0.54 | NQO1 (0.42) | ALDH1A1TSHRKMT2ATDP1L3MBTL1 | |
| Anthralin SCHEMBL3197 | 0.54 | MAPT (1.00) | MEN1USP2ALDH1A1HPNCYP3A4 | |
| Anthralin SCHEMBL29439039 | 0.54 | MAPT (1.00) | MEN1USP2ALDH1A1HPNCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504104-A | TREATING INFECTIONS OR DISEASES CAUSED BY RETROVIRUSES, SUCH AS HIV AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-02 | — | — | US | disclosed |