Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392780 | 0.78 | GRM2 (0.46) | FABP7FABP5ADAM17ADORA3 | |
| SCHEMBL15447425 | 0.74 | FABP7 (0.49) | FABP7FABP5PKMNPSR1ALDH1A1 | |
| SCHEMBL584437 | 0.74 | FABP7 (0.49) | FABP7FABP5PKMNPSR1ALDH1A1 | |
| SCHEMBL4966008 | 0.74 | ADAM17 (0.40) | DDB1CRBNADAM17MEN1KMT2A | |
| SCHEMBL7390481 | 0.73 | GRM2 (0.38) | FABP7FABP5ADAM17MEN1KMT2A | |
| SCHEMBL19323426 | 0.72 | CA1 (0.63) | CYP1A2TSHRCYP2C19FABP7FABP5 | |
| SCHEMBL20489039 | 0.71 | FABP7 (0.43) | CYP1A2TSHRCYP2C19FABP7FABP5 | |
| SCHEMBL25493720 | 0.71 | ALDH1A1 (0.55) | TSHRDDB1CRBNKMT2AALDH1A1 | |
| SCHEMBL31184719 | 0.70 | ALDH1A1 (0.54) | TSHRALDH1A1CA1CA2 | |
| SCHEMBL34472430 | 0.70 | ALDH1A1 (0.54) | TSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107342-A | 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives and a process for the preparation thereof | HOFFMANN-LA ROCHE INC. (US) | 2000-08-22 | — | — | US | disclosed |