Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392780 | 0.90 | GRM2 (0.46) | GRM2GRM3ADORA3ADAM17FABP7 | |
| SCHEMBL7385604 | 0.73 | CYP1A2 (0.40) | ADORA3ADAM17MEN1KMT2AFABP7 | |
| SCHEMBL5095260 | 0.71 | SLC6A3 (0.39) | GRM2GRM3 | |
| SCHEMBL7392651 | 0.68 | GRM2 (0.71) | GRM2GRM3 | |
| SCHEMBL7317711 | 0.68 | ADORA3 (0.37) | ADORA3ADAM17MEN1KMT2AFABP7 | |
| SCHEMBL12415464 | 0.67 | FABP7 (0.52) | KMT2AFABP7FABP5 | |
| SCHEMBL20489039 | 0.66 | FABP7 (0.43) | MEN1KMT2AFABP7FABP5 | |
| SCHEMBL15447425 | 0.66 | FABP7 (0.49) | FABP7FABP5 | |
| SCHEMBL584437 | 0.66 | FABP7 (0.49) | FABP7FABP5 | |
| SCHEMBL20731925 | 0.66 | GRM2 (0.42) | GRM2GRM3MEN1KMT2AFABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107342-A | 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives and a process for the preparation thereof | HOFFMANN-LA ROCHE INC. (US) | 2000-08-22 | — | — | US | disclosed |