Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391656 | 0.79 | TDP1 (0.51) | PDE3BPDE3ATSHRRXRARXRB | |
| SCHEMBL7282967 | 0.79 | CYP11B1 (0.44) | HRH3TDP1KDM4EALDH1A1 | |
| SCHEMBL7282199 | 0.79 | CYP11B1 (0.44) | HRH3TDP1KDM4EALDH1A1 | |
| SCHEMBL7393454 | 0.79 | EGFR (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL7283833 | 0.77 | ITGB3 (0.41) | HRH3 | |
| Hydrochloric Acid SCHEMBL7281759 | 0.77 | ITGB3 (0.41) | HRH3 | |
| SCHEMBL22922181 | 0.74 | CYP4F2 (0.59) | TSHRHRH3CYP4F2CYP4A11TDP1 | |
| SCHEMBL22996702 | 0.74 | HRH3 (0.38) | HRH3ADRB2ADRB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7390225 | 0.72 | RPS6KA3 (0.43) | HRH3CYP4F2CYP4A11ADRB2ADRB1 | |
| SCHEMBL2569441 | 0.71 | L3MBTL1 (0.55) | CYP4F2CYP4A11TDP1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |