Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700693 | 0.90 | CA1 (0.42) | TSHRHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL7699566 | 0.89 | LMNA (0.36) | TSHRHSD17B10KDM4EHPGDRECQL | |
| SCHEMBL7388616 | 0.85 | TSHR (0.45) | TSHRKDM4EHPGDALDH1A1MAPK1 | |
| SCHEMBL7695368 | 0.84 | ALDH1A1 (0.47) | TSHRHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL7382828 | 0.83 | L3MBTL1 (0.40) | TSHRHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL7388954 | 0.83 | ALDH1A1 (0.41) | TSHRHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL7702817 | 0.83 | ALDH1A1 (0.37) | TSHRKDM4EHPGDRECQLALDH1A1 | |
| SCHEMBL7697790 | 0.82 | ALDH1A1 (0.35) | TSHRHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL7883347 | 0.82 | L3MBTL1 (0.34) | TSHRKDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7385104 | 0.82 | NOTUM (0.40) | TSHRKDM4EALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055475-A1 | GUANIDINE DERIVIATIVES AS INHIBITORS OF NA+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |