Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 8/20 | 0.51 |
| ▸ | ALPL | P05186 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046606 | 0.78 | TP53 (0.57) | GAALMNAALOX15L3MBTL1POLB | |
| SCHEMBL7051619 | 0.77 | TP53 (0.60) | ALPLMAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL27706536 | 0.76 | TP53 (0.54) | MAPTGAALMNAALOX15HPGD | |
| SCHEMBL7386485 | 0.74 | TP53 (0.56) | ALPLMAPTGAALMNAHPGD | |
| SCHEMBL18926448 | 0.72 | GAA (0.58) | MAPTGAALMNAHPGDL3MBTL1 | |
| SCHEMBL10351730 | 0.72 | MAPT (0.58) | MAPTGAALMNAHPGDKDM4E | |
| SCHEMBL2522379 | 0.70 | LMNA (0.62) | GAALMNAALOX15L3MBTL1POLB | |
| SCHEMBL15622965 | 0.70 | NR1H4 (0.72) | MAPTGAALMNAL3MBTL1POLB | |
| SCHEMBL13856448 | 0.68 | ALPL (1.00) | ALPGALPLMAPTGAALMNA | |
| SCHEMBL2374361 | 0.67 | LMNA (0.58) | GAALMNAALOX15L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119351-A2 | USE OF CATECHOL DERIVATIVES AS PROTEINASE INHIBITORS | Grünenthal GmbH (DE) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000019989-A2 | USE OF CATECHOL DERIVATIVES AS PROTEINASE INHIBITORS | Grünenthal GmbH (DE) | 2000-04-13 | — | — | WO | disclosed |