Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379352 | 0.77 | TACR1 (0.49) | TACR1 | |
| SCHEMBL7379357 | 0.77 | TACR1 (0.49) | TACR1 | |
| SCHEMBL29222775 | 0.66 | MAPT (0.44) | — | |
| SCHEMBL27799875 | 0.65 | SIGMAR1 (0.58) | — | |
| SCHEMBL28917549 | 0.65 | SIGMAR1 (0.39) | TACR1 | |
| SCHEMBL30451454 | 0.65 | AGTR2 (0.58) | TACR1 | |
| Acetic Acid SCHEMBL7386447 | 0.64 | AGTR2 (0.54) | TACR1 | |
| SCHEMBL334587 | 0.64 | MAPT (0.40) | — | |
| SCHEMBL4190042 | 0.64 | ITGB3 (0.38) | — | |
| SCHEMBL7958970 | 0.64 | SIGMAR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348955-A | Angiotensis II antagonists | MERCK & CO., INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5292726-A | N,N-diacylpiperazines | MERCK & CO., INC. (US) | 1994-03-08 | — | — | US | disclosed |