Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391782 | 0.88 | ALDH1A1 (0.42) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7390764 | 0.81 | ALDH1A1 (0.41) | ALDH1A1NPSR1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL7384085 | 0.81 | NLRP3 (0.46) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL7384359 | 0.80 | GAA (0.42) | ALDH1A1HPGDNPSR1CYP1A2CYP2C19 | |
| SCHEMBL2059346 | 0.78 | MAPT (0.49) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7389902 | 0.78 | RECQL (0.43) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL5337411 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7391713 | 0.75 | NLRP3 (0.41) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7386893 | 0.75 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL4853186 | 0.74 | ALDH1A1 (0.45) | ALDH1A1NPSR1CYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |