Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391782 | 0.81 | ALDH1A1 (0.42) | RECQLHTTLMNAALDH1A1MAPT | |
| SCHEMBL7386893 | 0.81 | ALDH1A1 (0.44) | RECQLHTTLMNAALDH1A1MAPT | |
| SCHEMBL2059346 | 0.79 | MAPT (0.49) | GPR35LMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL31148932 | 0.79 | GPR35 (0.49) | GPR35LMNAALDH1A1MAPTESR1 | |
| SCHEMBL12817224 | 0.79 | GPR35 (0.49) | GPR35LMNAALDH1A1MAPTESR1 | |
| SCHEMBL7387482 | 0.78 | MAPT (0.40) | RECQLHTTLMNAALDH1A1MAPT | |
| SCHEMBL5345161 | 0.78 | ALDH1A1 (0.44) | RECQLHTTLMNAALDH1A1MAPT | |
| SCHEMBL7384359 | 0.78 | GAA (0.42) | ALDH1A1NPSR1HPGDCYP1A2CYP2C19 | |
| SCHEMBL3598134 | 0.76 | ALDH1A1 (0.50) | HTTLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL11241296 | 0.75 | RAB9A (0.49) | HTTGPR35LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |